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Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins

Cytolethal distending toxins (CDTs) are heterotrimeric protein exotoxins produced by a diverse array of Gram-negative pathogens. The enzymatic subunit, CdtB, possesses DNase and phosphatidylinositol 3-4-5 trisphosphate phosphatase activities that induce host cell cycle arrest, cellular distension an...

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Detalles Bibliográficos
Autores principales:	Dixon, Shandee D., Huynh, Melanie M., Tamilselvam, Batcha, Spiegelman, Lindsey M., Son, Sophia B., Eshraghi, Aria, Blanke, Steven R., Bradley, Kenneth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664275/ https://www.ncbi.nlm.nih.gov/pubmed/26618479 http://dx.doi.org/10.1371/journal.pone.0143977

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