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Dimethyl Fumarate Ameliorates Lewis Rat Experimental Autoimmune Neuritis and Mediates Axonal Protection

BACKGROUND: Dimethyl fumarate is an immunomodulatory and neuroprotective drug, approved recently for the treatment of relapsing-remitting multiple sclerosis. In view of the limited therapeutic options for human acute and chronic polyneuritis, we used the animal model of experimental autoimmune neuri...

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Detalles Bibliográficos
Autores principales: Pitarokoili, Kalliopi, Ambrosius, Björn, Meyer, Daniela, Schrewe, Lisa, Gold, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664277/
https://www.ncbi.nlm.nih.gov/pubmed/26618510
http://dx.doi.org/10.1371/journal.pone.0143416