The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Preserves Endothelial Function in Mesenteric Arteries from Type 1 Diabetic Rats without Decreasing Plasma Glucose

The aim of the study was to investigate the effect of the DPP-4 inhibitor linagliptin on the mechanism(s) of endothelium-dependent relaxation in mesenteric arteries from STZ-induced diabetic rats. Both normal and diabetic animals received linagliptin (2 mg/kg) daily by oral gavage for a period of 4...

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Detalles Bibliográficos
Autores principales: Salheen, Salheen M., Panchapakesan, Usha, Pollock, Carol A., Woodman, Owen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664283/
https://www.ncbi.nlm.nih.gov/pubmed/26618855
http://dx.doi.org/10.1371/journal.pone.0143941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664283/
https://www.ncbi.nlm.nih.gov/pubmed/26618855
http://dx.doi.org/10.1371/journal.pone.0143941

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