Cargando…

Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle

The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color variation, we modulated the expression of Tyrosinase (Tyr), which controls the rate-limiting step of melanogenesis, by expressing a single-co...

Descripción completa

Detalles Bibliográficos
Autores principales: Paterson, Elyse K., Fielder, Thomas J., MacGregor, Grant R., Ito, Shosuke, Wakamatsu, Kazumasa, Gillen, Daniel L., Eby, Victoria, Boissy, Raymond E., Ganesan, Anand K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664286/
https://www.ncbi.nlm.nih.gov/pubmed/26619124
http://dx.doi.org/10.1371/journal.pone.0143702