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Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle
The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color variation, we modulated the expression of Tyrosinase (Tyr), which controls the rate-limiting step of melanogenesis, by expressing a single-co...
Autores principales: | Paterson, Elyse K., Fielder, Thomas J., MacGregor, Grant R., Ito, Shosuke, Wakamatsu, Kazumasa, Gillen, Daniel L., Eby, Victoria, Boissy, Raymond E., Ganesan, Anand K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664286/ https://www.ncbi.nlm.nih.gov/pubmed/26619124 http://dx.doi.org/10.1371/journal.pone.0143702 |
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