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Inferring the Forces Controlling Metaphase Kinetochore Oscillations by Reverse Engineering System Dynamics

Kinetochores are multi-protein complexes that mediate the physical coupling of sister chromatids to spindle microtubule bundles (called kinetochore (K)-fibres) from respective poles. These kinetochore-attached K-fibres generate pushing and pulling forces, which combine with polar ejection forces (PE...

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Detalles Bibliográficos
Autores principales: Armond, Jonathan W., Harry, Edward F., McAinsh, Andrew D., Burroughs, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664287/
https://www.ncbi.nlm.nih.gov/pubmed/26618929
http://dx.doi.org/10.1371/journal.pcbi.1004607