Mapping Soluble Guanylyl Cyclase and Protein Disulfide Isomerase Regions of Interaction

Soluble guanylyl cyclase (sGC) is a heterodimeric nitric oxide (NO) receptor that produces cyclic GMP. This signaling mechanism is a key component in the cardiovascular system. NO binds to heme in the β subunit and stimulates the catalytic conversion of GTP to cGMP several hundred fold. Several endo...

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Detalles Bibliográficos
Autores principales: Heckler, Erin J., Kholodovych, Vladyslav, Jain, Mohit, Liu, Tong, Li, Hong, Beuve, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664405/
https://www.ncbi.nlm.nih.gov/pubmed/26618351
http://dx.doi.org/10.1371/journal.pone.0143523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664405/
https://www.ncbi.nlm.nih.gov/pubmed/26618351
http://dx.doi.org/10.1371/journal.pone.0143523

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