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Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype

Patient-individual tumor models constitute a powerful platform for basic and translational analyses both in vitro and in vivo. However, due to the labor-intensive and highly time-consuming process, only few well-characterized patient-derived cell lines and/or corresponding xenografts exist. In this...

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Detalles Bibliográficos
Autores principales: Maletzki, Claudia, Huehns, Maja, Knapp, Patrick, Waukosin, Nancy, Klar, Ernst, Prall, Friedrich, Linnebacher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664421/
https://www.ncbi.nlm.nih.gov/pubmed/26618628
http://dx.doi.org/10.1371/journal.pone.0143194