Cargando…
Functional Characterization and Drug Response of Freshly Established Patient-Derived Tumor Models with CpG Island Methylator Phenotype
Patient-individual tumor models constitute a powerful platform for basic and translational analyses both in vitro and in vivo. However, due to the labor-intensive and highly time-consuming process, only few well-characterized patient-derived cell lines and/or corresponding xenografts exist. In this...
Autores principales: | Maletzki, Claudia, Huehns, Maja, Knapp, Patrick, Waukosin, Nancy, Klar, Ernst, Prall, Friedrich, Linnebacher, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664421/ https://www.ncbi.nlm.nih.gov/pubmed/26618628 http://dx.doi.org/10.1371/journal.pone.0143194 |
Ejemplares similares
-
Ex-vivo Clonally Expanded B Lymphocytes Infiltrating Colorectal Carcinoma Are of Mature Immunophenotype and Produce Functional IgG
por: Maletzki, Claudia, et al.
Publicado: (2012) -
The mutational profile and infiltration pattern of murine MLH1(-/-) tumors: concurrences, disparities and cell line establishment for functional analysis
por: Maletzki, Claudia, et al.
Publicado: (2016) -
Cryopreservation of human colorectal carcinomas prior to xenografting
por: Linnebacher, Michael, et al.
Publicado: (2010) -
Preservation of methylated CpG dinucleotides in human CpG islands
por: Panchin, Alexander Y., et al.
Publicado: (2016) -
The CpG island methylator phenotype (CIMP) in colorectal cancer
por: Mojarad, Ehsan Nazemalhosseini, et al.
Publicado: (2013)