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Knockdown of a HIF-2α promoter upstream long noncoding RNA impairs colorectal cancer stem cell properties in vitro through HIF-2α downregulation

Currently, various long noncoding RNAs (lncRNAs) have been identified as key regulators of multiple cancers. However, cancer stem cell (CSC)-related lncRNAs have rarely been reported. In this study, we found an lncRNA that is a promoter upstream transcript of hypoxia-inducible factor-2α (HIF-2α), an...

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Detalles Bibliográficos
Autores principales: Yao, Jie, Li, Jianxiong, Geng, Peiliang, Li, Yi, Chen, Hong, Zhu, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664519/
https://www.ncbi.nlm.nih.gov/pubmed/26648739
http://dx.doi.org/10.2147/OTT.S81393