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Knockdown of a HIF-2α promoter upstream long noncoding RNA impairs colorectal cancer stem cell properties in vitro through HIF-2α downregulation
Currently, various long noncoding RNAs (lncRNAs) have been identified as key regulators of multiple cancers. However, cancer stem cell (CSC)-related lncRNAs have rarely been reported. In this study, we found an lncRNA that is a promoter upstream transcript of hypoxia-inducible factor-2α (HIF-2α), an...
Autores principales: | Yao, Jie, Li, Jianxiong, Geng, Peiliang, Li, Yi, Chen, Hong, Zhu, Yunfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664519/ https://www.ncbi.nlm.nih.gov/pubmed/26648739 http://dx.doi.org/10.2147/OTT.S81393 |
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