Development of polymeric–cationic peptide composite nanoparticles, a nanoparticle-in-nanoparticle system for controlled gene delivery

We report the formulation of novel composite nanoparticles that combine the high transfection efficiency of cationic peptide-DNA nanoparticles with the biocompatibility and prolonged delivery of polylactic acid–polyethylene glycol (PLA-PEG). The cationic cell-penetrating peptide RALA was used to con...

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Detalles Bibliográficos
Autores principales: Jain, Arvind K, Massey, Ashley, Yusuf, Helmy, McDonald, Denise M, McCarthy, Helen O, Kett, Vicky L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664533/
https://www.ncbi.nlm.nih.gov/pubmed/26648722
http://dx.doi.org/10.2147/IJN.S95245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664533/
https://www.ncbi.nlm.nih.gov/pubmed/26648722
http://dx.doi.org/10.2147/IJN.S95245

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