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Development of polymeric–cationic peptide composite nanoparticles, a nanoparticle-in-nanoparticle system for controlled gene delivery
We report the formulation of novel composite nanoparticles that combine the high transfection efficiency of cationic peptide-DNA nanoparticles with the biocompatibility and prolonged delivery of polylactic acid–polyethylene glycol (PLA-PEG). The cationic cell-penetrating peptide RALA was used to con...
Autores principales: | Jain, Arvind K, Massey, Ashley, Yusuf, Helmy, McDonald, Denise M, McCarthy, Helen O, Kett, Vicky L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664533/ https://www.ncbi.nlm.nih.gov/pubmed/26648722 http://dx.doi.org/10.2147/IJN.S95245 |
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