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Identification and Mechanistic Investigation of Drug–Drug Interactions Associated With Myopathy: A Translational Approach

Myopathy is a group of muscle diseases that can be induced or exacerbated by drug–drug interactions (DDIs). We sought to identify clinically important myopathic DDIs and elucidate their underlying mechanisms. Five DDIs were found to increase the risk of myopathy based on analysis of observational da...

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Detalles Bibliográficos
Autores principales: Han, X, Quinney, SK, Wang, Z, Zhang, P, Duke, J, Desta, Z, Elmendorf, JS, Flockhart, DA, Li, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664558/
https://www.ncbi.nlm.nih.gov/pubmed/25975815
http://dx.doi.org/10.1002/cpt.150