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Profiling of Sox4-dependent transcriptome in skin links tumour suppression and adult stem cell activation

Adult stem cells (ASCs) reside in specific niches in a quiescent state in adult mammals. Upon specific cues they become activated and respond by self-renewing and differentiating into newly generated specialised cells that ensure appropriate tissue fitness. ASC quiescence also serves as a tumour sup...

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Detalles Bibliográficos
Autores principales: Foronda, Miguel, Morgado-Palacin, Lucia, Gómez-López, Gonzalo, Domínguez, Orlando, Pisano, David G., Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664675/
https://www.ncbi.nlm.nih.gov/pubmed/26697322
http://dx.doi.org/10.1016/j.gdata.2015.07.030