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The pro-fibrotic and anti-inflammatory foam cell macrophage paradox

The formation of foamy macrophages by sequestering extracellular modified lipids is a key event in atherosclerosis. However, there is controversy about the effects of lipid loading on macrophage phenotype, with in vitro evidence suggesting either pro- or anti-inflammatory consequences. To investigat...

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Detalles Bibliográficos
Autores principales: Thomas, Anita C., Eijgelaar, Wouter J., Daemen, Mat J.A.P., Newby, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664709/
https://www.ncbi.nlm.nih.gov/pubmed/26697355
http://dx.doi.org/10.1016/j.gdata.2015.08.027