Defects in cytochrome c oxidase expression induce a metabolic shift to glycolysis and carcinogenesis

Mitochondrial metabolic dysfunction is often seen in cancers. This paper shows that the defect in a mitochondrial electron transport component, the cytochrome c oxidase (CcO), leads to increased glycolysis and carcinogenesis. Using whole genome microarray expression analysis we show that genetic sil...

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Detalles Bibliográficos
Autores principales: Dong, Dawei W., Srinivasan, Satish, Guha, Manti, Avadhani, Narayan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664720/
https://www.ncbi.nlm.nih.gov/pubmed/26697345
http://dx.doi.org/10.1016/j.gdata.2015.07.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664720/
https://www.ncbi.nlm.nih.gov/pubmed/26697345
http://dx.doi.org/10.1016/j.gdata.2015.07.031

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