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Global analysis of CPSF2-mediated alternative splicing: Integration of global iCLIP and transcriptome profiling data

Alternative splicing is a key mechanism for generating proteome diversity, however the mechanisms regulating alternative splicing are poorly understood. Using a genome-wide RNA interference screening strategy, we identified cleavage and polyadenylation specificity factor (CPSF) and symplekin (SYMPK)...

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Detalles Bibliográficos
Autores principales: Misra, Ashish, Ou, Jianhong, Zhu, Lihua Julie, Green, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664754/
https://www.ncbi.nlm.nih.gov/pubmed/26697379
http://dx.doi.org/10.1016/j.gdata.2015.09.022