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Global analysis of CPSF2-mediated alternative splicing: Integration of global iCLIP and transcriptome profiling data
Alternative splicing is a key mechanism for generating proteome diversity, however the mechanisms regulating alternative splicing are poorly understood. Using a genome-wide RNA interference screening strategy, we identified cleavage and polyadenylation specificity factor (CPSF) and symplekin (SYMPK)...
Autores principales: | Misra, Ashish, Ou, Jianhong, Zhu, Lihua Julie, Green, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664754/ https://www.ncbi.nlm.nih.gov/pubmed/26697379 http://dx.doi.org/10.1016/j.gdata.2015.09.022 |
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