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Understanding the physiology of the asymptomatic diaphragm of the M1592V hyperkalemic periodic paralysis mouse
The diaphragm muscle of hyperkalemic periodic paralysis (HyperKPP) patients and of the M1592V HyperKPP mouse model rarely suffers from the myotonic and paralytic symptoms that occur in limb muscles. Enigmatically, HyperKPP diaphragm expresses the mutant NaV1.4 channel and, more importantly, has an a...
Autores principales: | Ammar, Tarek, Lin, Wei, Higgins, Amanda, Hayward, Lawrence J., Renaud, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664826/ https://www.ncbi.nlm.nih.gov/pubmed/26621775 http://dx.doi.org/10.1085/jgp.201511476 |
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