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Composite Sequence–Structure Stability Models as Screening Tools for Identifying Vulnerable Targets for HIV Drug and Vaccine Development

Rapid evolution and high sequence diversity enable Human Immunodeficiency Virus (HIV) populations to acquire mutations to escape antiretroviral drugs and host immune responses, and thus are major obstacles for the control of the pandemic. One strategy to overcome this problem is to focus drugs and v...

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Detalles Bibliográficos
Autores principales: Manocheewa, Siriphan, Mittler, John E, Samudrala, Ram, Mullins, James I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664974/
https://www.ncbi.nlm.nih.gov/pubmed/26556362
http://dx.doi.org/10.3390/v7112901