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Cleavage of the HPV16 Minor Capsid Protein L2 during Virion Morphogenesis Ablates the Requirement for Cellular Furin during De Novo Infection

Infections by high-risk human papillomaviruses (HPV) are the causative agents for the development of cervical cancer. As with other non-enveloped viruses, HPVs are taken up by the cell through endocytosis following primary attachment to the host cell. Through studies using recombinant pseudovirus pa...

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Detalles Bibliográficos
Autores principales: Cruz, Linda, Biryukov, Jennifer, Conway, Michael J., Meyers, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664983/
https://www.ncbi.nlm.nih.gov/pubmed/26569287
http://dx.doi.org/10.3390/v7112910