Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications

Adenoviruses (Ad) are commonly used both experimentally and clinically, including oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the high rates of neutralizing immunity, estimated as high as 90% in some populations that promote vector clearance and limit...

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Detalles Bibliográficos
Autores principales: Uusi-Kerttula, Hanni, Hulin-Curtis, Sarah, Davies, James, Parker, Alan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664994/
https://www.ncbi.nlm.nih.gov/pubmed/26610547
http://dx.doi.org/10.3390/v7112923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664994/
https://www.ncbi.nlm.nih.gov/pubmed/26610547
http://dx.doi.org/10.3390/v7112923

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