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Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications
Adenoviruses (Ad) are commonly used both experimentally and clinically, including oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the high rates of neutralizing immunity, estimated as high as 90% in some populations that promote vector clearance and limit...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664994/ https://www.ncbi.nlm.nih.gov/pubmed/26610547 http://dx.doi.org/10.3390/v7112923 |