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CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors

An increasing number of noncoding RNAs (ncRNAs) have been implicated in various human diseases including cancer; however, the ncRNA transcriptome of hepatocellular carcinoma (HCC) is largely unexplored. We used CAGE to map transcription start sites across various types of human and mouse HCCs with e...

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Detalles Bibliográficos
Autores principales: Hashimoto, Kosuke, Suzuki, Ana Maria, Dos Santos, Alexandre, Desterke, Christophe, Collino, Agnese, Ghisletti, Serena, Braun, Emilie, Bonetti, Alessandro, Fort, Alexandre, Qin, Xian-Yang, Radaelli, Enrico, Kaczkowski, Bogumil, Forrest, Alistair R.R., Kojima, Soichi, Samuel, Didier, Natoli, Gioacchino, Buendia, Marie Annick, Faivre, Jamila, Carninci, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665003/
https://www.ncbi.nlm.nih.gov/pubmed/26510915
http://dx.doi.org/10.1101/gr.191031.115