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Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames
Mammalian gene expression displays widespread circadian oscillations. Rhythmic transcription underlies the core clock mechanism, but it cannot explain numerous observations made at the level of protein rhythmicity. We have used ribosome profiling in mouse liver to measure the translation of mRNAs in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665006/ https://www.ncbi.nlm.nih.gov/pubmed/26486724 http://dx.doi.org/10.1101/gr.195404.115 |