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Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames

Mammalian gene expression displays widespread circadian oscillations. Rhythmic transcription underlies the core clock mechanism, but it cannot explain numerous observations made at the level of protein rhythmicity. We have used ribosome profiling in mouse liver to measure the translation of mRNAs in...

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Detalles Bibliográficos
Autores principales: Janich, Peggy, Arpat, Alaaddin Bulak, Castelo-Szekely, Violeta, Lopes, Maykel, Gatfield, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665006/
https://www.ncbi.nlm.nih.gov/pubmed/26486724
http://dx.doi.org/10.1101/gr.195404.115

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