A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand Design

[Image: see text] Quorum sensing (QS) is a chemical signaling mechanism that allows bacterial populations to coordinate gene expression in response to social and environmental cues. Many bacterial pathogens use QS to initiate infection at high cell densities. Over the past two decades, chemical anta...

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Detalles Bibliográficos
Autores principales: Moore, Joseph D., Rossi, Francis M., Welsh, Michael A., Nyffeler, Kayleigh E., Blackwell, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665086/
https://www.ncbi.nlm.nih.gov/pubmed/26491787
http://dx.doi.org/10.1021/jacs.5b06728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665086/
https://www.ncbi.nlm.nih.gov/pubmed/26491787
http://dx.doi.org/10.1021/jacs.5b06728

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