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Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma

The encapsulation of miR-34a into chitosan/PLGA nanoparticles in order to obtain nanoplexes useful for the modulation of the biopharmaceutical features of the active compound was studied. The nanoplexes were obtained through nanoprecipitation and were characterized by a mean diameter of ~160 nm, a g...

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Detalles Bibliográficos
Autores principales: Cosco, Donato, Cilurzo, Felisa, Maiuolo, Jessica, Federico, Cinzia, Di Martino, Maria Teresa, Cristiano, Maria Chiara, Tassone, Pierfrancesco, Fresta, Massimo, Paolino, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665167/
https://www.ncbi.nlm.nih.gov/pubmed/26620594
http://dx.doi.org/10.1038/srep17579