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Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma
The encapsulation of miR-34a into chitosan/PLGA nanoparticles in order to obtain nanoplexes useful for the modulation of the biopharmaceutical features of the active compound was studied. The nanoplexes were obtained through nanoprecipitation and were characterized by a mean diameter of ~160 nm, a g...
Autores principales: | Cosco, Donato, Cilurzo, Felisa, Maiuolo, Jessica, Federico, Cinzia, Di Martino, Maria Teresa, Cristiano, Maria Chiara, Tassone, Pierfrancesco, Fresta, Massimo, Paolino, Donatella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665167/ https://www.ncbi.nlm.nih.gov/pubmed/26620594 http://dx.doi.org/10.1038/srep17579 |
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