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Loss of autophagy-related protein Beclin 1 may define poor prognosis in ovarian clear cell carcinomas

The aim of the present study was to clarify the role of autophagy in cisplatin (CDDP) sensitivity in OCCCs and the role of Beclin 1 in OCCC progression. Autophagy was measured using: i) western blot analysis of LC3 and p62 and ii) microscopic observation of GFP-LC3 puncta. Autophagy was suppressed u...

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Detalles Bibliográficos
Autores principales: KATAGIRI, HIROSHI, NAKAYAMA, KENTARO, RAZIA, SULTANA, NAKAMURA, KOHEI, SATO, EMI, ISHIBASHI, TOMOKA, ISHIKAWA, MASAKO, IIDA, KOUJI, ISHIKAWA, NORIYOSHI, OTSUKI, YOSHIRO, NAKAYAMA, SATORU, KYO, SATORU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665333/
https://www.ncbi.nlm.nih.gov/pubmed/26458502
http://dx.doi.org/10.3892/ijo.2015.3191