Antioxidant and Metal Chelation-Based Therapies in the Treatment of Prion Disease

Many neurodegenerative disorders involve the accumulation of multimeric assemblies and amyloid derived from misfolded conformers of constitutively expressed proteins. In addition, the brains of patients and experimental animals afflicted with prion disease display evidence of heightened oxidative st...

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Detalles Bibliográficos
Autores principales: Brazier, Marcus W., Wedd, Anthony G., Collins, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665489/
https://www.ncbi.nlm.nih.gov/pubmed/26784872
http://dx.doi.org/10.3390/antiox3020288