Antioxidant and Metal Chelation-Based Therapies in the Treatment of Prion Disease
Many neurodegenerative disorders involve the accumulation of multimeric assemblies and amyloid derived from misfolded conformers of constitutively expressed proteins. In addition, the brains of patients and experimental animals afflicted with prion disease display evidence of heightened oxidative st...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665489/ https://www.ncbi.nlm.nih.gov/pubmed/26784872 http://dx.doi.org/10.3390/antiox3020288 |