Cargando…
Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells
BACKGROUND: Two-hydroxyglutarate (2HG) is present at low concentrations in healthy mammalian cells as both an L and D enantiomer. Both the L and D enantiomers have been implicated in regulating cellular physiology by mechanisms that are only partially characterized. In multiple human cancers, the D...
Autores principales: | Gelman, Susan J., Mahieu, Nathaniel G., Cho, Kevin, Llufrio, Elizabeth M., Wencewicz, Timothy A., Patti, Gary J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665876/ https://www.ncbi.nlm.nih.gov/pubmed/26629338 http://dx.doi.org/10.1186/s40170-015-0139-z |
Ejemplares similares
-
Bar Coding MS(2) Spectra for Metabolite Identification
por: Spalding, Jonathan L., et al.
Publicado: (2016) -
Differential Incorporation of Glucose into Biomass
during Warburg Metabolism
por: Chen, Ying-Jr, et al.
Publicado: (2014) -
Sorting cells alters their redox state and cellular metabolome
por: Llufrio, Elizabeth M., et al.
Publicado: (2018) -
Profiling cancer metabolism at the ‘omic’ level: a last resort or the next frontier?
por: Gelman, Susan J., et al.
Publicado: (2016) -
2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia
por: Fitzpatrick, Susan F., et al.
Publicado: (2020)