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Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer

BACKGROUND: Karyopherin alpha 2 (KPNA2), a member of the karyopherin family, plays a vital role in carcinogenesis. Yet its role in colon cancer is poorly characterized. We sought to clarify the clinical significance of its dysregulated expression in human colon tumor specimens. METHODS: We evaluated...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhang, Meng, Yu, Fudong, Lu, Su, Sun, Huimin, Tang, Huamei, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665890/
https://www.ncbi.nlm.nih.gov/pubmed/26626145
http://dx.doi.org/10.1186/s13046-015-0261-3