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Genetic diversity of transmission-blocking vaccine candidate Pvs48/45 in Plasmodium vivax populations in China
BACKGROUND: The male gamete fertilization factor P48/45 in malaria parasites is a prime transmission-blocking vaccine (TBV) candidate. Efforts to develop antimalarial vaccines are often thwarted by genetic diversity of the target antigens. Here we evaluated the genetic diversity of Pvs48/45 gene in...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665908/ https://www.ncbi.nlm.nih.gov/pubmed/26627683 http://dx.doi.org/10.1186/s13071-015-1232-4 |