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Genetic diversity of transmission-blocking vaccine candidate Pvs48/45 in Plasmodium vivax populations in China

BACKGROUND: The male gamete fertilization factor P48/45 in malaria parasites is a prime transmission-blocking vaccine (TBV) candidate. Efforts to develop antimalarial vaccines are often thwarted by genetic diversity of the target antigens. Here we evaluated the genetic diversity of Pvs48/45 gene in...

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Detalles Bibliográficos
Autores principales: Feng, Hui, Gupta, Bhavna, Wang, Meilian, Zheng, Wenqi, Zheng, Li, Zhu, Xiaotong, Yang, Yimei, Fang, Qiang, Luo, Enjie, Fan, Qi, Tsuboi, Takafumi, Cao, Yaming, Cui, Liwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665908/
https://www.ncbi.nlm.nih.gov/pubmed/26627683
http://dx.doi.org/10.1186/s13071-015-1232-4