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Comparative assessment of native and heterologous 2-oxo acid decarboxylases for application in isobutanol production by Saccharomyces cerevisiae

BACKGROUND: Decarboxylation of α-ketoisovalerate to isobutyraldehyde is a key reaction in metabolic engineering of Saccharomyces cerevisiae for isobutanol production with published studies relying on overexpression of either the native ARO10 gene or of the Lactococcus lactis kivD decarboxylase gene...

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Detalles Bibliográficos
Autores principales: Milne, N., van Maris, A. J. A., Pronk, J. T., Daran, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665922/
https://www.ncbi.nlm.nih.gov/pubmed/26628917
http://dx.doi.org/10.1186/s13068-015-0374-0