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Prediction of solution properties and dynamics of RNAs by means of Brownian dynamics simulation of coarse-grained models: Ribosomal 5S RNA and phenylalanine transfer RNA

BACKGROUND: The possibility of validating biological macromolecules with locally disordered domains like RNA against solution properties is helpful to understand their function. In this work, we present a computational scheme for predicting global properties and mimicking the internal dynamics of RN...

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Detalles Bibliográficos
Autores principales: Benítez, Aarón Ayllón, Hernández Cifre, José Ginés, Díaz Baños, Francisco Guillermo, de la Torre, José García
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666080/
https://www.ncbi.nlm.nih.gov/pubmed/26629336
http://dx.doi.org/10.1186/s13628-015-0025-7