Bounding the per-protocol effect in randomized trials: an application to colorectal cancer screening

BACKGROUND: The per-protocol effect is the effect that would have been observed in a randomized trial had everybody followed the protocol. Though obtaining a valid point estimate for the per-protocol effect requires assumptions that are unverifiable and often implausible, lower and upper bounds for...

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Detalles Bibliográficos
Autores principales: Swanson, Sonja A., Holme, Øyvind, Løberg, Magnus, Kalager, Mette, Bretthauer, Michael, Hoff, Geir, Aas, Eline, Hernán, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666083/
https://www.ncbi.nlm.nih.gov/pubmed/26620120
http://dx.doi.org/10.1186/s13063-015-1056-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666083/
https://www.ncbi.nlm.nih.gov/pubmed/26620120
http://dx.doi.org/10.1186/s13063-015-1056-8

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