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GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival

Although TrkA postendocytic sorting significantly influences neuronal cell survival and differentiation, the molecular mechanism underlying TrkA receptor sorting in the recycling or degradation pathways remains poorly understood. Here we demonstrate that Golgi-localized, γ adaptin-ear–containing ADP...

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Detalles Bibliográficos
Autores principales: Li, Xuezhi, Lavigne, Pierre, Lavoie, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666136/
https://www.ncbi.nlm.nih.gov/pubmed/26446845
http://dx.doi.org/10.1091/mbc.E15-02-0087