Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3

Cilia are important organelles formed by cell membrane protrusions; however, little is known about their regulation by membrane lipids. We characterize a novel activation mechanism for glycogen synthase kinase-3 (GSK3) by the sphingolipids phytoceramide and ceramide that is critical for ciliogenesis...

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Detalles Bibliográficos
Autores principales: Kong, Ji Na, Hardin, Kara, Dinkins, Michael, Wang, Guanghu, He, Qian, Mujadzic, Tarik, Zhu, Gu, Bielawski, Jacek, Spassieva, Stefka, Bieberich, Erhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666139/
https://www.ncbi.nlm.nih.gov/pubmed/26446842
http://dx.doi.org/10.1091/mbc.E15-06-0371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666139/
https://www.ncbi.nlm.nih.gov/pubmed/26446842
http://dx.doi.org/10.1091/mbc.E15-06-0371

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