Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson’s disease

Parkinson’s disease (PD) is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidal motor dysfunction. Recent evidence indicates that cyclin-dependent kinase 5 (Cdk5) is inappropriat...

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Detalles Bibliográficos
Autores principales: Binukumar, BK., Shukla, Varsha, Amin, Niranjana D., Grant, Philip, Bhaskar, M., Skuntz, Susan, Steiner, Joseph, Pant, Harish C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666141/
https://www.ncbi.nlm.nih.gov/pubmed/26399293
http://dx.doi.org/10.1091/mbc.E15-06-0415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666141/
https://www.ncbi.nlm.nih.gov/pubmed/26399293
http://dx.doi.org/10.1091/mbc.E15-06-0415

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