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Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditions

INTRODUCTION: Bone marrow-derived mesenchymal stem cells (BM-MSCs) for clinical use should not be grown in media containing fetal bovine serum (FBS), because of serum-related concerns over biosafety and batch-to-batch variability. Previously, we described the preparation and use of a cell-free nativ...

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Detalles Bibliográficos
Autores principales: Rakian, Rubie, Block, Travis J., Johnson, Shannan M., Marinkovic, Milos, Wu, Junjie, Dai, Qiuxia, Dean, David D., Chen, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666167/
https://www.ncbi.nlm.nih.gov/pubmed/26620283
http://dx.doi.org/10.1186/s13287-015-0235-6