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Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditions
INTRODUCTION: Bone marrow-derived mesenchymal stem cells (BM-MSCs) for clinical use should not be grown in media containing fetal bovine serum (FBS), because of serum-related concerns over biosafety and batch-to-batch variability. Previously, we described the preparation and use of a cell-free nativ...
Autores principales: | Rakian, Rubie, Block, Travis J., Johnson, Shannan M., Marinkovic, Milos, Wu, Junjie, Dai, Qiuxia, Dean, David D., Chen, Xiao-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666167/ https://www.ncbi.nlm.nih.gov/pubmed/26620283 http://dx.doi.org/10.1186/s13287-015-0235-6 |
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