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Novel avian single-chain fragment variable (scFv) targets dietary gluten and related natural grain prolamins, toxic entities of celiac disease

BACKGROUND: Celiac disease (CD) is a chronic, small intestinal inflammatory disease mediated by dietary gluten and related prolamins. The only current therapeutic option is maintenance of a strict life-long gluten-free diet, which implies substantial burden for CD patients. Different treatment regim...

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Detalles Bibliográficos
Autores principales: Stadlmann, Valerie, Harant, Hanna, Korschineck, Irina, Hermann, Marcela, Forster, Florian, Missbichler, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666168/
https://www.ncbi.nlm.nih.gov/pubmed/26625857
http://dx.doi.org/10.1186/s12896-015-0223-z