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Epistasis analysis links immune cascades and cerebral amyloidosis

BACKGROUND: Several lines of evidence suggest the involvement of neuroinflammatory changes in Alzheimer’s disease (AD) pathophysiology such as amyloidosis and neurodegeneration. In fact, genome-wide association studies (GWAS) have shown a link between genes involved in neuroinflammation and AD. In o...

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Detalles Bibliográficos
Autores principales: Benedet, Andréa L., Labbe, Aurélie, Lemay, Philippe, Zimmer, Eduardo R., Pascoal, Tharick A., Leuzy, Antoine, Mathotaarachchi, Sulantha, Mohades, Sara, Shin, Monica, Dionne-Laporte, Alexandre, Beaudry, Thomas, Picard, Cynthia, Gauthier, Serge, Poirier, Judes, Rouleau, Guy, Rosa-Neto, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666175/
https://www.ncbi.nlm.nih.gov/pubmed/26626881
http://dx.doi.org/10.1186/s12974-015-0436-z