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Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes

BACKGROUND: In the central nervous system, glial cells provide metabolic and trophic support to neurons and respond to protracted stress and insults by up-regulating inflammatory processes. Reactive astrocytes and microglia are associated with the pathophysiology of neuronal injury, neurodegenerativ...

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Detalles Bibliográficos
Autores principales: Daniele, Simona, Zappelli, Elisa, Martini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666178/
https://www.ncbi.nlm.nih.gov/pubmed/26627476
http://dx.doi.org/10.1186/s12974-015-0446-x