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ADMIRE: analysis and visualization of differential methylation in genomic regions using the Infinium HumanMethylation450 Assay

BACKGROUND: DNA methylation at cytosine nucleotides constitutes epigenetic gene regulation impacting cellular development and a wide range of diseases. Cytosine bases of the DNA are converted to 5-methylcytosine by the methyltransferase enzyme, acting as a reversible regulator of gene expression. Du...

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Detalles Bibliográficos
Autores principales: Preussner, Jens, Bayer, Julia, Kuenne, Carsten, Looso, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666223/
https://www.ncbi.nlm.nih.gov/pubmed/26628921
http://dx.doi.org/10.1186/s13072-015-0045-1