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Intrastrand triplex DNA repeats in bacteria: a source of genomic instability

Repetitive nucleic acid sequences are often prone to form secondary structures distinct from B-DNA. Prominent examples of such structures are DNA triplexes. We observed that certain intrastrand triplex motifs are highly conserved and abundant in prokaryotic genomes. A systematic search of 5246 diffe...

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Detalles Bibliográficos
Autores principales: Holder, Isabelle T., Wagner, Stefanie, Xiong, Peiwen, Sinn, Malte, Frickey, Tancred, Meyer, Axel, Hartig, Jörg S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666352/
https://www.ncbi.nlm.nih.gov/pubmed/26450966
http://dx.doi.org/10.1093/nar/gkv1017