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Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5′-3′ exoribonuclease) in the nucleoplasm

Collaborator of alternative reading frame protein (CARF) associates directly with ARF, p53, and/or human double minute 2 protein (HDM2), a ubiquitin-protein ligase, without cofactors and regulates cell proliferation by forming a negative feedback loop. Although ARF, p53, and HDM2 also participate in...

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Detalles Bibliográficos
Autores principales: Sato, Shigeko, Ishikawa, Hideaki, Yoshikawa, Harunori, Izumikawa, Keiichi, Simpson, Richard J., Takahashi, Nobuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666357/
https://www.ncbi.nlm.nih.gov/pubmed/26531822
http://dx.doi.org/10.1093/nar/gkv1069