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Collaborator of alternative reading frame protein (CARF) regulates early processing of pre-ribosomal RNA by retaining XRN2 (5′-3′ exoribonuclease) in the nucleoplasm
Collaborator of alternative reading frame protein (CARF) associates directly with ARF, p53, and/or human double minute 2 protein (HDM2), a ubiquitin-protein ligase, without cofactors and regulates cell proliferation by forming a negative feedback loop. Although ARF, p53, and HDM2 also participate in...
Autores principales: | Sato, Shigeko, Ishikawa, Hideaki, Yoshikawa, Harunori, Izumikawa, Keiichi, Simpson, Richard J., Takahashi, Nobuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666357/ https://www.ncbi.nlm.nih.gov/pubmed/26531822 http://dx.doi.org/10.1093/nar/gkv1069 |
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